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New research identifies a mechanism of action for the GLP-1 receptor, the target of GLP-1 diabetes drugs Research led by Imperial has uncovered a hidden cellular mechanism that explains how widely used type 2 diabetes drugs signal to protect the pancreas, opening up new possibilities for improving future diabetes therapies

Curr Ther Res Clin Exp

While the study concluded that short-term DSIP treatment was unlikely to be of major therapeutic benefit noting that statistically significant effects were weak and partly attributable to incidental placebo group change it provided the most methodologically rigorous human sleep architecture dataset for DSIP and confirmed the compounds specific effect on objective, not merely subjective, sleep quality parameters

N Engl J Med 1990;322:223-8.ArticlePubMed 59