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In a rat anterior-cruciate-ligament reconstruction model, intra-articular GHK-Cu produced a transient improvement in graft stiffness at six weeks, which disappeared once treatment stopped
Studies suggest IO flushing is uniformly painful -especially tibial sites - and lidocaine may help, data remains limited
Once the needle is in place, the anesthetic and steroid medication is injected into the muscle
The results demonstrated a highly concentrated distribution of the time to the inflection point (i.e., the onset of the logarithmic growth phase) within each group, confirming the excellent detection reproducibility of the system
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