Lymphedema, a chronic condition causing progressive limb swelling from impaired lymphatic drainage, affects approximately 1-2 million Americans and remains challenging to manage
J Physiol Pharmacol 66(6):773778 Ma J, Hu X, Zhang W, Tao M, Wang M, Lu W (2025) Comparison of the effects of liraglutide, tirzepatide, and retatrutide on diabetic kidney disease in db/db mice
Mounjaro patients in trials lost an average of 15-22% of body weight over 72 weeks Wegovy patients lost an average of 12-15% over 68 weeks Most patients notice a reduction in appetite within the first two to four weeks Weight loss is generally gradual and steady
For weight management, reassessment should include evaluation of body composition changes rather than scale weight alone, as patients may be gaining muscle mass while losing fat, particularly if they have increased physical activity