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Common side effects shared by both medications: Nausea (most common, usually transient peaks during dose escalation) Vomiting Diarrhea or constipation Decreased appetite and early satiety Bloating or stomach discomfort Injection site reactions Key safety warnings that apply to both drugs: FDA Boxed Warning (both): Possible risk of thyroid C-cell tumors, based on animal studies

3 Evidence suggests that the number of prescriptions for these drugs has increased significantly