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ROS exacerbate the severity of asthma symptoms by activating inflammatory mediators that cause airway smooth muscle contraction, promote mucus hypersecretion, increase the permeability of lung capillaries, and damage cell membranes

Reassess with blood work at 3-month intervals during maintenance to guide continuation decisions

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As previously discussed, disturbances in iron metabolism play a critical role the pathophysiology following aSAH, with abnormal increases in intracellular ferrous iron serving as a key initiating factor of ferroptosis (51)