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the accumulation of reactive oxygen species (ROS) including superoxide and hydrogen peroxide, which results in lipid peroxidation and development of visible necrotic lesions (hypersensitive response, HR) ( via thiol-disulfide redox reactions (Noctor et al., 2012

While not FDA-approved for longevity enhancement, its used in supervised medical protocols for healthspan optimization and biological age management

Eligible publications included peer-reviewed original research articles, encompassing in vivo and in vitro experimental studies, randomized controlled trials, observational clinical studies, and mechanistically relevant translational investigations

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