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Substrates for furin cleavage possess a specific 20-residue recognition sequence motif, which includes: pro- parathyroid hormone (PTH), transforming growth factor (TGF)-1 precursor, pro - albumin , membrane type-1 matrix metalloproteinase (MMP), -subunit of pro- nerve growth factor , and von Willebrand factor 337

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If pigmentation is the primary concern, lasers, IPL, or chemical peels usually form the foundation

Incremental prognostic significance of peripheral endothelial dysfunction in patients with heart failure with normal left ventricular ejection fraction