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To understand the photo-activation process in more detail, we performed small-angle X-ray scattering (SAXS) measurements using the dark and light states of the full-length protein (SASBDB SASDUS3 and SASDUT3 respectively)

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Disclaimer: These findings are derived from non-human studies

In metabolic cages, acyl-GIP reduced food intake across the 12-h dark period, associated with a significant reduction in the RER in control Gipr AP-GFP but not Gipr AP-KO mice (Fig