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The second reason is from the neuroscience field
doi: 10.1038/s41467-024-46691-0 Summary Keywords extrachromosomal circular DNA (eccDNA), functional genomics, non-Mendelian inheritance, phenotypic plasticity, rapid adaptation, stress tolerance Citation MacGregor DR and Saski CA (2026) Extrachromosomal circular DNA are functional, heritable units that expand genomic plasticity and confer resilience
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