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In a retrospective study of serum 25(OH)D levels in 648 children with epilepsy in China, the serum 25(OH)D level in children with epilepsy was reduced both before and during ASMs treatment, and the SF was significantly reduced in the group treated with ASMs and receiving vitamin D supplements (120)

In addition to their potent metabolic actions that reduce hyperglycaemia and body weight, GLP-1RAs also lower the risk of major kidney, cardiovascular and mortality outcomes across broad populations with cardiovascular disease or CKD, with and without diabetes or obesity

The results provide new mechanistic insight into association of metabolic and cardiovascular comorbidities with gout and hyperuricemia