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Animal studies have examined whether Epithalon administration helps restore age-related declines in melatonin rhythm, offering a model for studying circadian disruption and its downstream metabolic effects, including sleep architecture and hormonal signaling that shift with advancing age

In 2004, oncologist Jim Olson was dismayed to discover that even after a 14-hour surgery to remove a tumor from a teenage girl's brain, a thumb-sized piece of the cancer had been left behind