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Sglt2 inhibitor luseogliflozin rapidly normalizes aortic mRNA levels of inflammation-related but not lipid-metabolism-related genes and suppresses atherosclerosis in diabetic Apo E KO mice

The combination creates a molecule with remarkable biological activity

10.1016/j.fertnstert.2012.05.031 7

[1] Since then, it has become one of the most studied hormones in metabolic medicine and the biological basis for some of the most talked-about diabetes and weight-loss drugs in the world, like Ozempic