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In the results, the cells containing pCNFRS-TSDV showed a significant improvement in the fluorescence intensity compared to the wild type pCNFRS, while the misincorporation of canonical amino acids was weakly decreased (Fig

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However, in a large randomized controlled trial (ESCAPE-NA1) [61] published in 2020, the rate of favorable functional outcome at 90 days in patients undergoing endovascular thrombectomy was not significantly different with NA-1 compared with the control group, which represented a failure of clinical translation

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