Historically, obesity was stigmatized and under-treated, often perceived as a result of poor lifestyle choices rather than as a complex metabolic condition
It now includes oral GLP-1 drugs, amylin combinations, dual agonists, triple agonists, long-acting platforms, and differentiated assets designed for durability, tolerability, access, or broader metabolic indications
The National Institute for Health and Care Excellence (NICE) guideline NG28 recognises both drug classes as treatment options within the type 2 diabetes management pathway
Modrzejewska-Sikorska A, Robakowska M, Konowa E, Gojzewski H, Gierz , Wieczorek B et al (2023) Lignin and starch derivatives with selenium nanoparticles for the efficient reduction of dyes and as polymer fillers