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While the treatment with Ru(II)-OH or NP2 slightly elevated the ROS levels inside the hypoxic cancer cells, the treatment with NP4 showed a strong enhancement of ROS

Patrick J

When treated with 5FU, cancer cells specifically increase mitochondrial content to buffer nucleotide stress, whereas stromal cells do not, meaning that cancer cells become intrinsically more dependent on mitochondrial metabolism

1000166, 2016, [4] J
