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In order to generate this model and induce PCOS-like traits in adult offspring, pregnant dams were administered with a daily dose of the androgen dihydrotestosterone (DHT, 250 g/day) during gestational days 16, 17, and 18
Additionally, GLP-1RAs ameliorate DPN through various mechanisms, including the inhibition of inflammation, oxidative stress, and extracellular matrix remodeling, while simultaneously improving neural structure, function, and energy metabolism [11, 12, 30, 79,80,81,82,83,84,85,86]
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