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GLP-1 agonists showed effects on reward responses during anticipation and consumption of food rewards in lean participants (caudate, OFC), in participants with obesity (OFC) and in participants with T2D (putamen, insula, amygdala) (van Bloemendaal et al., 2015a)
The SUSTAIN 6 trial, another key study, examined semaglutide's impact on cardiovascular outcomes in patients with type 2 diabetes
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