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One study suggests that the decrease in vagal signaling seen with HFD feeding is due to upregulation of K+ channels in the nodose ganglia, increasing hyperpolarization of VANs 67 , while other studies have implicated changes in the gut microbiota as a contributor to vagal afferent desensitization during HFD feeding (see the Gut microbiotabrain connection section)
Weight gain after breast cancer diagnosis and all-cause mortality: systematic review and meta-analysis
mTORC1 activity is inhibited in conditions of energy depletion coordinated with AMPK activity
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