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This article reviews the efficacy and safety of different strategies to initiate and intensify basal insulin, with focus on new fixed ratio combinations of basal insulin with GLP-1 RAs available for use in a single injection pen (insulin degludec/liraglutide and insulin glargine/lixisenatide)
A BPC-157 and TB-500 nasal spray product, by contrast, will likely not replicate the same level and consistency of bioavailability compared to subcutaneous injection
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