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The researchers then looked at whether women were diagnosed with a new breast cancer in two different cohorts: the full group of 111,646 women and a smaller cohort of 30,528 women, including one-to-one controls for each of the 15,264 GLP-1 cases, matched across age, race, ethnicity, BMI, breast density, and diabetes status to limit bias and potential confounding
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Additionally, disruptions in the balance of glutamate and its interaction with other neurotransmitters, such as GABA and serotonin, which are involved in the flow of glutamate between the cortex, thalamus, and basolateral amygdala, may result in abnormal CSTC pathway activity (14)
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