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It is engineered with two structural modifications relative to the 70-residue native protein: a substitution of arginine for glutamic acid at the third position and a 13-amino-acid extension at the N-terminus, giving a total length of 83 amino acids
However, xanthine could also be salvaged through the purine salvage pathway and used as a backbone for the synthesis of purine nucleosides, guanosine, and adenosine [68]
doi:10.2147/CEG.S181590 [20] McFarlin BK, Henning AL, Bowman EM, Gary MA, Carbajal KM
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