Integrating the proteomic and metabolic datasets, we discovered that enzymes pivotal to cysteine biosynthesis, such as cystathionine beta-synthase (CBS) [27], and key glutathione biosynthesis genes, including glutamate-cysteine ligase catalytic subunit (GCLC) [28] and Glutamate-cysteine ligase regulatory subunit (GCLM) [29], were key downstream targets downregulated upon DDX3X inhibition (Fig
Salinity stress ranging from 0.6 to 3.2 dSm 1 directly disrupts crop production and electrical conduction of salt 9
If the liver produces enough glutathione, it can exit acetaldehyde (alcohol turned into toxic acid in the liver) quickly from the body
Maity, S., Farrell, K., Navabpour, S., Narayanan, S