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Modified Factor VII may be encoded by a polynucleotide molecule comprising two operatively linked sequence coding regions encoding, respectively, a pre-pro peptide and a gla domain of a vitamin K-dependent plasma protein, and a gla domain-less Factor VII protein, wherein upon expression said polynucleotide encodes a modified Factor VII molecule which does not significantly activate plasma Factors X or IX, and is capable of binding tissue factor

PMID: 39680480 Cell Rep Med Enhancing gastric cancer immunotherapy: Insights from multi-omics analysis and innovations in photodynamic-chemotherapy nanoplatforms

It seems that DPP-4i decreased GLP-1 expression in lung tissues form rats with PH in the present study, but it is not the fact

These damaged proteins can become joined together through a mechanism called crosslinking, which causes increased stiffness and loss of elasticity in several tissues throughout the body (Nawale 2006