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Using this route, released glutamate is almost quantitatively taken up by astrocytes (Danbolt, 2001), and either converted to glutamine and reintroduced in the glutamineglutamate (GABA) cycle, or metabolized to -ketoglutarate by glutamate-dehydrogenase (GDH) or aspartateglutamate transferase (AAT), followed by -ketoglutarate oxidation after malate exit and decarboxylation

The human PIK3C3 protein forms a heterodimer with a regulatory subunit that is designated p150 (Vps15 in yeast) which is encoded by the PIK3R4 gene

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Evidence-based complementary and alternative medicine: eCAM