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One way of screening for sensitivity to primaquine is based on the observation that the glutathione concentration of erythrocytes from sensitive subjects is somewhat lower than that of control subjects, and falls considerably on incubation with acetylphenylhydrazine

In controlled laboratory models, researchers use GHK-Cu to investigate extracellular matrix (ECM) remodeling, copper balance in cells, and redox signaling (how cells respond to oxidative stress)