Sekhars years-long expertise, knowledge and interest in metabolic disorders affecting HIV patients and a parallel track investigating non-HIV people have resulted in the publication of significant discoveries regarding the metabolic complications in aging, HIV and diabetes, and has guided numerous clinical trials that together provide a better understanding of why we age
Key References Wilding JPH, Batterham RL, Calanna S, Davies M, Van Gaal LF, Lingvay I, et al
GLP-1 medications may not be appropriate for individuals with a personal or family history of medullary thyroid carcinoma or MEN2 syndrome, history of pancreatitis, pregnancy or breastfeeding, BMI under 27 without weight-related comorbidities, or those who haven't yet tried structured lifestyle changes
In their primary analysis, they evaluated changes in total and free testosterone using pair nonparametric testing and performed an adjust linear analysis that controlled for age and BMI