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Randomized controlled studies of oral vitamin B12 therapy in vitamin B12 deficiency Several prospective randomized controlled studies comparing oral vitamin B12 vs
By inhibiting NNMT, 5-Amino-1MQ may spare nicotinamide for NAD+ synthesis via the salvage pathway, thereby activating SIRT1 (Sirtuin 1) pathways associated with mitochondrial biogenesis, fat oxidation, and metabolic flexibility [3]
