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Oxylipin A large class of bioactive lipid metabolites derived from the oxidation of polyunsaturated fatty acids

By potentially stabilizing delta sleep phases, DSIP is studied in contexts examining how neural recovery interacts with endocrine restoration

Early inflammation necessary for debris clearance and infection prevention, but prolonged inflammation damages tissues

Because FOXO4-DRIs mechanism depends on disrupting the FOXO4p53 interaction, and because this interaction is only operative in cells with elevated FOXO4 expression, the compound preferentially targets the senescent cell population leaving FOXO4-low non-senescent cells largely unaffected