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Outside of those major clinical trials, a nationwide retrospective study in Taiwan, China, evaluated the effects of DPP-4i in elderly patients with T2DM relative to cardiovascular outcomes

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TB-500 is reported with a longer serum half-life (often cited around 2.53 hours after subcutaneous administration) and prolonged tissue availability, which is why research protocols conventionally model it on a less frequent schedule

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GIP is secreted by the K-cells in the small intestine and plays a role in glucose metabolism

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