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229 Clinical trials in postmenopausal women have found a 0.5% vaginal DHEA preparation providing 6.5 mg of DHEA per day or 50 mg of oral DHEA effectively reduced symptoms of genitourinary syndrome of menopause without stimulating the endometrium, and may reduce hot flashes and menopausal symptoms

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proved, through an in vivo study with model rats and an in vitro study using organotypic hippocampal slice cultures, that nicotinamide mononucleotide improved learning and memory in Alzheimers disease rats while also reducing the accumulation of ROS and cell death in organotypic hippocampal slice cultures