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Effects of liraglutide in the treatment of obesity in women with polycystic ovary syndrome
Patients with kidney disease require careful medical evaluation and baseline lab work before starting any GLP-1 medication, as these compounds affect hydration status and renal perfusion
2016;150:1088A
The strategy was, therefore, to identify GLP-1 mimetic drugs with a molecular structure close enough to native GLP-1 to stimulate the GLP-1 receptor, but with alterations that enabled prolonged activity by, in particular, possessing resistance to breakdown by DPP-4 (Meier, 2012)
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