A larger follow-up RCT (n=72 older adults) confirmed these findings, additionally demonstrating improvements in gait speed (+0.14 m/s), grip strength, 6-minute walk distance, waist circumference reduction, and systolic blood pressure reduction (Kumar et al., J Gerontol A Biol Sci Med Sci, 2023) [21]
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Exposure to heat degrades the active ingredient, reducing the medication's ability to regulate appetite and blood sugar
For instance, the SKSC222 strain, engineered with a synthetic isozyme system, achieved 2.0 g/L of glutathione with a volumetric productivity of 29.85 mg/L/h under fed-batch fermentation conditions (Jeon et al., 2023)