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Several substituted derivatives of hydroxylamine are known and, it has been shown that one of them, N-tert-butyl hydroxylamine, protects cells from OS and mitochondrial damage in an in vitro model of age-related macular degeneration (AMD) [285]
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Gene expression profiling revealed distinct apoptotic pathways: low-dose exposure triggers apoptosis through cellular stress responses, while high-dose exposure primarily activates it via direct DNA damage (160)
PMID: 26408528 Headley DB et al (2006): Different subcellular distributions of the vesicular monoamine transporter, VMAT2, in subclasses of sympathetic neurons
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