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Suh JH, Shenvi SV, Dixon BM, Liu H, Jaiswal AK, Liu RM, Hagen TM (2004) Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid

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FDA-approved Crohn's treatments include biologic therapies (infliximab, adalimumab, vedolizumab, ustekinumab, risankizumab), JAK inhibitors (upadacitinib), corticosteroids for induction (budesonide, prednisone), and immunomodulators (azathioprine, methotrexate)

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