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Targeting both GLP-1 and insulin secretion with a SSTR5 antagonist could perhaps be an advantage in the treatment of hyperglycemia in humans
Wegovy is an FDA-approved injectable medication containing semaglutide that helps people lose weight by reducing appetite and increasing feelings of fullness
Tirzepatide adds GIP receptor activation to the GLP-1 pathway, offering dual hormone signaling that may provide weight loss benefits while maintaining a similar gastrointestinal safety profile
Am.J Clin Oncol
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