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c normally resides within the cristae of the IMM and is sequestered by narrow cristae junctions

Glutathione colorimetric assay is rapid and can be used to measure concentrations of reduced glutathione (GSH), oxidized glutathione (GSSG) and total glutathione (GSH+GSSG) in wide range of samples such as, blood, plasma, serum, cultured cells and tissue

GT-activated prodrugs and potential nephrotoxicity Gamma-glutamyl transferase being the initial and limiting step in GT-activated prodrugs processing and because GT is highly expressed on the luminal surface of the proximal tubules in the kidney, potential nephrotoxicity could have been a limitation in the usage of this class of compound when administered systematically

GI, gastrointestinal