i took tirzepatide while pregnant Mounjaro (tirzepatide) side effects & how to treat them Injection Site Bruising After Tirzepatide:

Although the difference in the incidence of MACE between GLP-1 RA and comparators failed to show statistical significance (Mantel-Haenzel odds ratio, 0.78

Hormonal changes may cause cyclical weight variations of 2-5 pounds and affect appetite, fluid retention, and metabolic rate independent of medication effects

Combined with the concurrent upregulation of dimethylargininase, which degrades an inhibitor of nitric oxide synthase, has been associated with augmented neovascularization, and was overexpressed 1.5-fold (p=0.002) in semaglutide-treated animals, this constitutes substantial evidence of the relevance of the nitric oxide biosynthetic pathway to an account of the cardiac effects of semaglutide

3 It is assumed that GLP-1 may be involved in the stimulation of glucose disposal in peripheral tissues independent of insulin actions, the researchers note