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People who used the medications also exhibited reduced risk for other adverse outcomes, including sickle cell crisis, venous thromboembolism, ischemic stroke or transient ischemic attack, and cardiopulmonary complications

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What Both Medications Do Inside the Body Although the delivery systems differ, both medications activate the GLP-1 receptor and trigger similar downstream effects: Increased insulin release in response to elevated blood sugar Reduced glucagon secretion Slower gastric emptying Reduced appetite signaling Increased satiety after meals According to the National Institute of Diabetes and Digestive and Kidney Diseases, these mechanisms can support improved blood sugar regulation and meaningful weight reduction when combined with lifestyle interventions

Endocrinology 150, 11221131 (2009)