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Both L-carnitine loss into the dialysate and impaired synthesis by the kidneys contribute to a progressive carnitine deficiency in patients with end-stage renal disease (ESRD) undergoing hemodialysis (71)
Results Identification of GPX4 Allosteric Activator In the previous study, we have identified a potential allosteric site in the crystal structure of human GPX4 U46C mutant (hGPX4-C, PDB entry 2OBI
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