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(4)(5) Opioid receptors : Further research indicates that DSIP might indirectly affect opioid receptors in the brain

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Your pituitary (the small gland at the base of your brain that releases GH) isnt held in a prolonged on state, it pulses, then resets, then is ready for the next natural signal

It's found in relatively high concentrations in several bodily tissues and plays critical roles in mitigating oxidative stress and inflammation, maintaining redox balance, enhancing metabolic detoxification processes, and regulating immune function 2