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Proposed mechanisms include: DSIP-induced upregulation of downstream receptor systems that outlast the peptide itself
We then hypothesized that the inefficacy of the peptide in inducing cell death in both types of cells might be attributed to inadequate cellular uptake
IA Donat, Sardjoko , PN Vermeulen - Cytotoxic and cytoprotective activities of curcumin
The activation and proliferation of glial cells, in turn, are useful in order to release signaling factors and to trigger a robust immune reaction consisting of brain-resident as well as peripherally recruited inflammatory cells
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