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Sodiumglucose co-transporter 2 (SGLT2) inhibitors exert hypoglycaemic effects by inhibiting glucose reabsorption at the proximal convoluted tubules, causing glycosuria, natriuresis and volume contraction (Figure 1).5 Besides SGLT2 inhibition, incretin-based therapies have also been used in recent years for the treatment of T2D ( Figure 2 )

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J Diabetes Investig (2020) 11(2):2657

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Libraries were quantified with NuQuant, quality checked using a TapeStation instrument (Agilent Technologies) and subjected to 52 bp paired-end sequencing on the NovaSeq 6000 system (Illumina)

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