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Patients considering GLP-1 receptor agonist or dual GIP/GLP-1 therapy should understand that these medications facilitate weight loss through appetite reduction and decreased food intake, not by "speeding up metabolism" or burning additional calories at rest
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As noted, endogenous GLP-1 has a very short half-life of 12 min because it is rapidly degraded by the enzyme DPP-4, which results in low systemic levels
is a potent antioxidant that helps neutralize free radicals, protecting cells from oxidative stress and damage
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