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Your stomach is holding food longer than your brain expects, creating a mismatch between what your gut signals and what your central nervous system interprets as normal

However, as this was an observational target trial emulation conducted in a predominantly male Veterans Affairs population, the results support but do not establish causality and may have limited generalisability to broader populations, particularly women and non-veteran groups

Freeze-thaw considerations When you move a frozen aliquot to the refrigerator, you are performing one controlled thaw

Consumers should be wary of dietary supplements claiming to contain GLP-1 or promising "GLP-1-like" effects, as these claims are not FDA-approved and lack scientific validity