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Ethics declarations Ethical approval The animal was handled and treated in accordance to general guidelines and regulations approved by the Forschungsinstitut fr Nutztierbiologie (FBN) authority
The rhythmic release of GH secreted by the pituitary gland is controlled by growth hormone-releasing hormone and somatostatin in the hypothalamus ( Regulation of Circadian Clock System on the GH/IGF-1 Axis Human GH (hGH) transgenic mice were used to express the hGH gene in mouse pituitary somatotrophs (Vakili et al., 2016)
In: Sperling MA (ed), Pediatric Endocrinology
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