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To date pathogenic variants in at least 12 different genes have been shown to contribute to type 2 RTA
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Similarly, treatment of murine RAW 264.7 cells with E2 blunted LPS/IFN-induced reductions in basal oxidative phosphorylation, and this was associated with reduced TNF- and increased IL-10 secretion compared to cells treated with LPS/IFN
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