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12 weeks 84 syringes 1 syringe per day
In the phase 2 NEJM 2023 trial, the net glycaemic effect of retatrutide was favourable improvements in fasting glucose and insulin resistance markers were observed suggesting that the insulin-stimulating effects of GLP-1R and GIPR agonism counterbalanced any glucose-raising tendency from glucagon receptor activation
However, its a big leap from a mouse study to recommending GLP-1 drugs for human athletes
If you are wondering about the differences between semaglutide and tirzepatide , that comparison involves an entirely different class of dual-agonist medications
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