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Constriction of blood vessels and platelet aggregation, followed by phagocytosis to produce inflammation at the targeted site, are the characteristics of this phase (Oguntibeju, 2019), which occurs due to the release of inflammatory particles such as histamine, prostaglandin, and leukotrienes to promote angiogenesis and cell permeability at the site of the wound (Jonidi Shariatzadeh et al., 2025)
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[2] Lau, D.C., et al
The clinical application requires understanding both the peptide's mechanisms and appropriate dosing strategies for specific conditions
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