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In parallel, studies have reported modulation of early growth response-1 (EGR-1) expression and its regulatory partner NAB2, which are involved in cytokine signaling and early extracellular matrix formation during cellular response processes [2]
These findings are consistent with the in vitro results that GLP-1 induces AMPK phosphorylation, inhibits PARP-1, therefore increasing LXR-mediated ABCA1 expression
Iran J Basic Med Sci
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