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Importantly, the combination therapy did not lead to a higher incidence of adverse reactions, with rates of 8.89% in the observation group versus 20.00% in the control group
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Notably, 1 O exihibits a high degree of chemical reactivity, allowing it to directly target lipids, proteins, and DNA in cell membranes, thereby inducing oxidative damage [88]
Novel analogues and even dual-agonist/tri-agonist drugs in the pipeline may require further capacity in the next decade
